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C-QuIPS Research

Core and affiliated members engage in a broad range of research, mostly in the acute care setting, but also focused on improved care coordination and transitions across settings of care. Specific research topics include clinical informatics, medication safety, usability and human factors engineering, fatigue, handoffs between providers, innovative models for teaching the concepts and methods of quality improvement, and improving methods for identifying patient safety problems.

Some research highlights appear below followed by a more detailed analysis of research productivity.

Dr. Chris Parshuram (paediatric research lead for C-QuIPS) received a $3.3M award from the Canadian Institutes for Health Research (CIHR) to conduct a multi-centre cluster randomized trial of the "The Bedside Paediatric Warning System" which he has developed over the past several years. The trial includes 22 hospitals in Canada, the US, and New Zealand.

Prof. Ross Baker was part of a $1.3M CIHR-funded project to conduct a national study of adverse events in the home care setting—the first national study to apply the methods of previous adverse event research to characterize the types of preventable harms experienced by patients receiving home-based care. The first main results from this study were recently published with an accompanying editorial and a press release from the Canadian Patient Safety Institute (CPSI).

Drs. Brian Wong and Kaveh Shojania, along with several other core members of the Centre, including Dr. Ed Etchells and Prof. Ross Baker, received the highest ranking in the Canadian Patient Safety Institute's annual grant program, for a study entitled Promoting Real-Time Improvements in Safety for the Elderly (PRISE).

Dr. Anne Matlow led a multi-centre team, including Prof. Ross Baker, Dr. Trey Coffey, and Virginia Flintoft from the Centre, to conduct the first national paediatric adverse event study. The main paper presenting the study's appeared in the CMAJ.

Dr. Ed Etchells led a team, including several members of the Centre (Drs. Shojania and Anne Matlow) that successfully obtained the award associated with a Request for Proposals from CPSI to evaluate the economic burden of patient safety problems and cost-effectiveness assessments of patient safety interventions.

Dr. Shojania is on the core project team (as the Scientific Chair) for Building Bridges to Integrate Care, a $5M program by the UofT Departments of Medicine and Family and Community Medicine at the University of Toronto and funded by the Ontario Ministry of Health and Long-term Care. BRIDGES supports the evaluation of nine innovative models of care delivery with an emphasis on reducing avoidable hospitalizations through better care coordination for patients with chronic illnesses.

Dr. Shojania was part of the core project team on a $1M contract from the US Agency for Healthcare Research and Quality (AHRQ) to produce a comprehensive set of systematic reviews evaluating the effectiveness of patient safety interventions. The project involved investigators at 5 AHRQ Evidence-based Practice Centers funded by (RAND-UCLA, Stanford, University of California San Francisco, Johns Hopkins University, and the non-profit research institute ECRI (Emergency Care Research Institute). Annals of Internal Medicine published multiple papers from this work as a supplement in Feb 2013.

Dr. Trey Coffey leads the sole Canadian site in $2M, 10-site study funded by the US Department of Health and Human Services to implement and evaluate a structured patient handoff program for clinical trainees.

Dr. Shojania became the Editor-in-Chief of BMJ Quality and Safety in January 2011. Published by the British Medical Journal, BMJQS accepts only 18% of the roughly 1000 manuscripts received each year and has the highest impact factor of any of the journals in the fields of patient safety and quality improvement. Two C-QuIPS faculty members, Dr. Chaim Bell and Prof. Ann Tourangeau, are Associate Editors at the journal.